Enzymes and Inhibitors
Medchemexpress LLC Gly-Pro-AMC hydrobromide | 115035-46-6 | 98.68% | 410.26 | 25 MG
Gly-Pro-AMC hydrobromide is a fluorescent dye that serves as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity. It is intended for research use only.
- Fluorescent dye
- Specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity
- Fluorescence detection conditions: excitation wavelength 350 nm, fluorescence emission spectrum detection 450 nm
Abcam L-alpha-Phosphatidylinositol, Phospholipase C substrate, 250MG
MW 867.14 g/mol. Phospholipase C substrate. Phospholipid membrane component. Inositol phosphate precursor. Stimulates vascular Ca²+-dependent protease autolysis.
The product is subject to the following: Abcam Restricted Use Statement
Gold Biotechnology Inc 1g
Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivoat 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.
Aniara Diagnostica LLC BIOPHEN CS-01(38) THROMB 12 EA
This item MFG by HYPHEN BioMed and Dis. by Aniara Diagnostics. Chromogenic substrate for thrombin, lyophilized. Peptide sequence H-D-Phe-Pip-Arg-pNa, 2HCl. 12 vials x 25 mg.
Biotium Coelenterazine (ALSO KNOWN AS NATIVE COE
Coelenterazines are luminescent enzyme substrates for apoaequorin and Renilla luciferase. Apoaequorin is used as a calcium indicator whereas Renilla luciferase is commonly used as a reporter of transcription regulation. Coelenterazine binds apoaequorin to form an aequorin complex which emits light upon calcium binding, and can measure a broad range of calcium concentrations from ~0.1 uM to >100 uM. Renilla luciferase is widely used as a reporter protein and as a donor in bioluminescence resonance energy transfer (BRET) to study protein-protein interactions. Coelenterazines can also be used for chemiluminescent detection of superoxide anion and peroxynitrite in cells or tissues.Coelenterazine (native): Yellow solid soluble in MeOH or EtOH; Store at -20°C and protect from light; C26H21N3O3; MW: 423; [55779-48-1]. See also other Coelentrazine analogs and water-soluble Aquaphile™ Coelenterazines (native and analog h) for in vivo use.
Ubpbio Ac-ANW-AMC, 5MG
Ac-ANW-AMC is a fluorogenic substrate of the chymotrypsin-like activity of proteasomes. This substrate is preferentially cleaved by immunoproteasomes compared to constitutive proteasomes. The AMC fluorescence can be detected by a fluorimeter or a plate reader using excitation/emission wavelengths at 360 nm/460 nm, respectively. This substrate can be used to determine the chymotrypsin-like activity of immunoproteasomes. Working concentration is 50 - 200 µM.
Sino Biological Peptide Substrates: TGFBR1 Peptide
The TGFBR1 peptide sequence (KKKVLTQMGSPSIRC-S(pS)VS) is derived from human SMAD3 (215-230) and is suitable for use as the substrate for TGFBR1 superfamily, including ACVRs (ALK1, ALK2, ALK4 and ALK7) and BMPRs (ALK3 and ALK6).
Medchemexpress LLC Recombinant canine HER2 (CD340/ERBB2) protein, C-terminal His tag | >95.0% | 2 UG
Recombinant canine HER2 (ERBB2/CD340) protein comprising residues T23-T652 with a C-terminal His tag, produced in HEK293 cells and supplied lyophilized. Supplied as a purified extracellular/truncated form for use in antibody binding studies, assay development, and signaling research. Manufacturer reconstitution and storage guidance should be followed.
- Purity greater than 95% by reducing SDS-PAGE.
- Expressed in HEK293 cells for native-like glycosylation.
- C-terminal His tag facilitates detection and purification.
- Lyophilized from PBS (pH 7.4) for improved stability.
- Store at -20°C; reconstitute to ≥100 μg/mL and aliquot for long-term storage.
Cayman Chemical CyclIc AMP TR-FRET KIt 1ea
Designed to allow the user to detect and quantitatively measure the amount of cyclic AMP (cAMP) present in cell based assay systems.
Abcam H-Met-AMC, Calpain substrate, 100MG
MW 420.4 g/mol, Purity >99%. Calpain substrate. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Sino Biological Peptide Substrates: GSK3 Substrate
The GSK3 sub peptide sequence (YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE) is based on human muscle glycogen synthase 1 (amino acid 636-661).
Apexbio Technology LLC D-Luciferin(Synonyms: Firefly Luciferin, Luciferin, Beetle Luciferin, (S)-2-(6'-Hydroxybenzothiazolyl)-Δ2-thiazoline-4-carboxylic acid), 10mg, CAS: 2591-17-5.
D-Luciferin (CAS 2591-17-5) is a membrane-permeable bioluminescent substrate for firefly luciferase characterized by a Km of approximately 2 M In the presence of ATP luciferin undergoes oxidation and decarboxylation catalyzed by luciferase emitting measurable photons This bioluminescence enables quantification of intracellular ATP levels both in vitro and in vivo In biomedical research D-Luciferin is commonly applied for monitoring promoter-driven luciferase gene expression and as a non-invasive imaging probe in bioluminescence imaging (BLI) studies to assess tumor burden pharmacodynamics and cellular ATP content
Cayman Chemical Boc-Lys Ac-AMC 5mg
A fluorogenic HDAC substrate; ex/em = 340-360/440-460 nm, respectively; following deacetylation by an HDAC and trypsin cleavage, AMC is released and its fluorescence can be used to quantify HDAC activity
Abcam 5-CFDA (5-Carbo x yfluorescein Diacetate), Fluorogenic non-selective esterase substrate, 100MG
MW 460.4 Da, Purity >95%. Hydrophobic, cell-permeable fluorogenic non-selective esterase substrate. Becomes hydrolyzed to hydrophilic strongly fluorescent 5-Carboxyfluorescein (ab145293) intracellularly. Measures intracellular pH. 5-CFDA N-succinimidyl ester (ab145292) precursor.
The product is subject to the following: Abcam Restricted Use Statement